Faculty
Jorge R. Oksenberg, Ph.D.
Professor in the Department of Neurology,
University of California at San Francisco (UCSF)
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Dr. Oksenberg is the G.A. Zimmermann Endowed Chair in Neurology. Dr. Oksenberg received his Ph.D. in Immunology from the Hebrew University of Jerusalem, Israel, and joined the UCSF faculty in 1993 following post-doctoral training at Stanford University. For more than 18 years Dr. Oksenberg has investigated the immunologic, molecular, and genetic mechanisms affecting MS susceptibility and disease course. He authored numerous publication and scholarly reviews in the field. Dr. Oksenberg is a leading investigator in the multi-center Multiple Sclerosis Genetics Group and the International Multiple Sclerosis Genetics Consortium. Since 2005, Dr. Oksenberg serves as Associate Editor for the Annals of Neurology.
Stephen L. Hauser, M.D
Professor and Chair of the Department of Neurology
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Dr. Hauser is a graduate of Massachusetts Institute of Technology and the Harvard Medical School. He trained in internal medicine at the New York Hospital/Cornell Medical Center and in neurology at the Massachusetts General Hospital/Harvard Medical School. Following postdoctoral fellowships in immunology at Harvard Medical School and the Institut Pasteur in Paris, France, he joined the faculty at Harvard and established an independent laboratory at the Massachusetts General Hospital. Since 1992, he has served as chairman and Robert A. Fishman Distinguished Professor of the Department of Neurology at UCSF. Dr. Hauser’s research has focused on MS. He was responsible for one of the first clinical trials of immunosuppression on the course of progressive MS. His early work identified the CD4 T-cell as important in MS and also in experimental models of demyelination. With colleagues, he developed the first animal model that faithfully reproduces the neuropathology of MS and identified an autoantibody against a quantitatively minor myelin protein, myelin oligodendrocyte glycoprotein, that mediated myelin damage. During the past decade he has also led a multicenter effort to identify the major genes that confer susceptibility to MS. He is a fellow of the American Academy of Arts and Sciences and the American Association of Physicians, a member of the Institute of Medicine and serves as an editor of the medical textbook Harrison’s Principles of Internal Medicine and Chief Editor of the Annals of Neurology.
Sergio Baranzini, Ph.D
Assistant Professor at the Department of Neurology, UCSF
Dr. Baranzini has over 15 years of experience working in human genetics projects. His initial research focused on genotype-phenotype correlations in Mendelian disorders. Since 1997 Dr. Baranzini has been involved in gene expression analysis and his current research focuses on characterizing the molecular mechanisms of homeostasis and disease in the context of human and experimental demyelination. To this end, he uses a combination of “wet lab” methods including DNA microarrays, proteomics, and laser capture microdissection, in combination with “dry lab” analytical approaches encompassing bioinformatics, complexity theory, and mathematical modeling.
Bruce C. Cree, M.D., Ph.D.
Assistant Professor of Neurology,
University of California San Francisco Multiple Sclerosis Center
Dr. Cree is board certified in neurology. After graduating from Brown University, Providence, Rhode Island, Dr. Cree earned his medical degree and his PhD from the University of California San Francisco. He completed his residency in Neurology at New York Presbyterian Hospital (Columbia University), New York City, where he was chief resident. He returned to UCSF where he undertook postdoctoral subspecialty training in multiple sclerosis as a Sylvia Lawry fellow. Additionally, he received a Master’s degree in Clinical Research. Dr. Cree has served as an investigator on numerous clinical studies in multiple sclerosis. Much of his research has focused on multiple sclerosis epidemiology and outcomes.