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Multiple Sclerosis Research Group

Publications

Recent Publications

Byun E., S.J. Caillier, X. Montalban, P. Villoslada, O. Fernández, D. Brassat, M. Comabella, J. Wang, L.F. Barcellos, S.E. Baranzini, J.R. Oksenberg. Genome-wide pharmacogenomic analysis of the response to interferon beta therapy in multiple sclerosis. Arch Neurol. In press.
PMID: 18195134

International Multiple Sclerosis Genetics Consortium. Risk alleles for multiple sclerosis identified by a genomewide study. New Engl. J. Med. 357:851-862, 2007.
PMID: 17660530

Begovich A.B., M. Chang, S.J. Caillier, D. Lew, J.J. Catanese, J. Wang, S.L. Hauser, J.R. Oksenberg. The autoimmune disease-associated IL12B and IL23R polymorphisms in multiple sclerosis. Hum Immunol. 68:934-937, 2007.
PMID: 18082575

Gregory S., S. Schmidt, P. Seth, J.R. Oksenberg, J. Hart, A. Prokop, S.J Caillier, M. Ban, A. Goris, L.F. Barcellos, R. Lincoln, J.L. McCauley, S.J Sawcer, D.A.S. Compston, B. Dubois, S.L. Hauser, M.A. Garcia-Blanco, M.A. Pericak-Vance, J.L. Haines. Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis. Nature Genet. 39:1083-1091, 2007.
PMID: 17660817

Pedemonte E., F. Benvenuto, S. Casazza, G. Mancardi, J.R. Oksenberg, A. Uccelli, S.E. Baranzini. The molecular signature of therapeutic mesenchymal stem cells exposes the architecture of the hematopoietic stem cell niche synapse. BMC Genomics 8:65, 2007.
PMID: 17341312

Fernald G.H., S. Knott, A. Pachner, S.J. Caillier, K. Narayan, J.R. Oksenberg, P. Mousavi, S.E. Baranzini, Genome-wide network analysis reveals the global properties of IFN-beta immediate transcriptional effects in humans. J. Immunol. 178:5076-5085, 2007.
PMID: 17404290

Barbour J.D., U. Sriram, S.J. Caillier, J.A. Levy, F.M Hecht, J.R. Oksenberg. Synergy or independence? Deciphering the interaction of HLA class I and NK cell KIR alleles in early HIV-1 disease progression. PLoS Pathogens 3:471-474 2007.
PMID: 17447840

Dunn S., S.S. Ousman, R.A. Sobel, L. Zuniga, S.E. Baranzini, S. Youssef, A. Crowell, J. Loh, J.R. Oksenberg, L Steinman. Peroxisome Proliferator Activated Receptor (PPAR)-α expression in T cells mediates gender differences in development of T cell-mediated autoimmunity. J. Exp. Med. 23:741:747, 2007.
PMID: 17261635

International Multiple Sclerosis Genetics Consortium. A second MHC susceptibility locus for multiple sclerosis. Ann. Neurol. 61:228-236, 2007.
PMID: 17252545

Sriram U., M. Wong, S.J. Caillier, F.M. Hecht, M.K. Elkins, J.A. Levy, J.R. Oksenberg, S.E. Baranzini. Quantitative longitudinal analysis of T cell receptor repertoire expression in HIV-infected patients on antiretroviral and interleukin-2 therapy. J. AIDS. 23:741-747, 2007.
PMID: 17531001

Motsinger A.A., D. Brassat, S.J. Caillier, H.A. Erlich, K. Walker, L.L. Steiner, B.A.C. Cree, L.F. Barcellos, M.A. Pericak-Vance, S. Schmidt, S. Gregory, Stephen L. Hauser, J.L. Haines, J.R. Oksenberg, M.D. Ritchie. Complex gene-gene interactions in multiple sclerosis: a multi-factorial approach reveals associations with inflammatory genes. Neurogenetics. 8:11-20, 2007.
PMID: 17024427

Barcellos L.F., S. Sawcer, P.P. Ramsay, S.E. Baranzini, G. Thomson, F. Briggs, B.C.A. Cree, A.B. Begovich, P. Villoslada, X. Montalban, A. Ucelli, G. Savatierri, R.L. Lincoln, C. DeLoa, J.L. Haines, M.A. Pericak-Vance, A. Compston, S.L. Hauser, J.R. Oksenberg Heterogeneity at the HLA-DRB1 locus and the risk for multiple sclerosis. Hum. Molec. Genet. 15:2913-1825, 2006.
PMID: 16905561

Barcellos L.F., B.B. Kamdar, P.P. Ramsay, C. DeLoa, R.R. Lincoln, S. Caillier, S. Schmidt, J.L. Haines, M.A. Pericak-Vance, J.R. Oksenberg, S.L. Hauser. Clustering of autoimmune diseases in high risk for multiple sclerosis families: a descriptive study. Lancet Neurology. 5:924-931, 2006.
PMID: 17052659

Schmidt S., M.A. Pericak-Vance, S. Sawcer, L.F. Barcellos, J. Hart , J. Sims, A.M. Prokop, C. DeLoa, R.R. Lincoln, J.R. Oksenberg, A.D. Compston, S.L. Hauser, J.L. Haines, S.G. Gregory. Allelic association of sequence variants in the herpes virus entry mediator-B gene (PVRL2) with the severity of multiple sclerosis. Genes and Immunity. 7:384-392, 2006.
PMID: 16738668

Brassat D., A.A. Motsinger, S.J. Caillier, H.A. Erlich, K. Walker, L.L. Steiner, B.A.C. Cree, L.F. Barcellos, M.A. Pericak-Vance, S. Schmidt, S. Gregory, S.L. Hauser, J.L. Haines, J.R. Oksenberg, M.D. Ritchie. Multifactor Dimensionality Reduction reveals gene-gene interactions associated with multiple sclerosis susceptibility in African Americans. Genes and Immunity. 7:310-315, 2006.
PMID: 16625214

Traherne J.A., L.F. Barcellos, S.J. Sawcer, D.A.S. Compston, P.P. Ramsay, S.L. Hauser, J.R. Oksenberg, J.A. Trowsdale. BTNL2 association with multiple sclerosis is secondary to HLA-DRB1*15. Hum. Molec. Genet. 15:155-161, 2006.
PMID: 16321988